Developing a biochemical assay is one of the first steps in launching a drug discovery program. While initial screens often rely on a single assay technology, the use of orthogonal assays offers an opportunity to confidently validate hits revealed in the primary screen. Complementary assays can inform on compound potency, selectivity, and mechanism of action, guiding decisions on which compounds should progress towards pre-clinical evaluation.
Learn how SAMDI Tech simultaneously developed multiple, orthogonal assays to assure a drug discovery company they could progress initial hits immediately into multiple assay formats to validate their activity, determine selectivity, and ensure a promising mechanism of action.