SAMDI ASMS: High-Throughput Screening for PROTAC and Molecular Glues
Targeted protein degradation (TPD) is a promising therapeutic mechanism to engage challenging and previously intractable protein targets. Modalities such as…
Integrating Machine Learning in Drug Discovery: A Balancing Act of Intelligent Decisions and Artificial Results
One of the major challenges in small molecule drug discovery is the significant attrition rate of compounds through drug development….
How ASMS Offers More Than Seeing What Sticks
The ability to rapidly identify small molecules that non-covalently bind to a specific target is a critical tool that will…
Webinar: Integrating Affinity Selection Mass Spectrometry (ASMS) Into a Drug Discovery Workflow
Abstract High-throughput screening remains one of the most powerful, unbiased approaches in drug discovery for revealing novel small molecule modulators…
High-Throughput Affinity Selection Mass Spectrometry (ASMS) Using SAMDI-MS to Identify Small-Molecule Binders of the Human Rhinovirus 3C Protease
Abstract Affinity selection mass spectrometry (ASMS) has emerged as a powerful high-throughput screening tool used in drug discovery to identify…
Blog – Integrating Affinity Selection Mass Spectrometry (ASMS) in a Drug Discovery Workflow
High-throughput screening remains one of the most powerful, unbiased approaches in drug discovery for revealing novel small molecule modulators of…
Pairing the Right Small Molecule Library with Innovative High-Throughput Screening Creates More Therapeutic Opportunity
An important step in initiating a high-throughput screening project is selecting the small molecule library to be screened against the…
Ultra High-Throughput Affinity Selection Mass Spectrometry (ASMS) Assays
SAMDI Affinity Selection Mass Spectrometry (ASMS)
SAMDI Affinity Selection Mass Spectrometry is a universal approach for the discovery of small molecules that bind specifically to target…