Integrating affinity selection mass spectrometry in a drug discovery workflow
High-throughput screening remains one of the most powerful, unbiased approaches in drug discovery for revealing novel small molecule modulators of…
Partnering With Service Providers: Challenges and Solutions
Many biotech and pharmaceutical companies rely on service providers or contract research organizations (CROs) for drug discovery and development services….
Four Tips for Selecting a Small Molecule Screening Library
High-throughput screening remains one of the most powerful, unbiased approaches in drug discovery for revealing small molecule modulators of biochemical…
Radioactivity Assays for Methyltransferases
Methyltransferases have emerged as valuable therapeutic targets in cancer and other pathologies. This enzyme class includes protein and RNA methyltransferases…
Ultra High-Throughput Affinity Selection Mass Spectrometry Assays
The Fast and Victorious: Level Up Your Drug Discovery With Innovative Mass Spectrometry
Mass Spectrometry Gaining Momentum for Biochemical Assay Development and Screening
The goal of drug discovery is clear: reveal chemical matter that generates the most effective response towards a particular target…
Application of MALDI-MS for HTS and SAR
Disrupting Drug Discovery Research From Assay Development to Lead Compound
High-throughput screening remains one of the most powerful, unbiased approaches for small molecule drug discovery. Today, the toolbox for high-throughput…
Label-Free Phosphatase Assays
Phosphatases are enzymes that catalyze the removal of phosphate groups from distinct substrates. They can be broadly characterized into classes…