Webinar – Integrating Affinity Selection Mass Spectrometry (ASMS) Into a Drug Discovery Workflow
Abstract High-throughput screening remains one of the most powerful, unbiased approaches in drug discovery for revealing novel small molecule modulators…
Development of a Novel Label-Free and High-Throughput Arginase-1 Assay Using Self-Assembled Monolayer Desorption Ionization Mass Spectrometry
Abstract Arginase-1, an enzyme that catalyzes the reaction of L-arginine to L-ornithine, is implicated in the tumor immune response and…
Going Above and Beyond in Drug Discovery: Orthogonal Assays Aid in Selecting Promising Drug Leads
Developing a biochemical assay is one of the first steps in launching a drug discovery program. While initial screens often…
Blog – Integrating Affinity Selection Mass Spectrometry (ASMS) in a Drug Discovery Workflow
High-throughput screening remains one of the most powerful, unbiased approaches in drug discovery for revealing novel small molecule modulators of…
Partnering With Service Providers: Challenges and Solutions
Many biotech and pharmaceutical companies rely on service providers or contract research organizations (CROs) for drug discovery and development services….
Pairing the Right Small Molecule Library with Innovative High-Throughput Screening Creates More Therapeutic Opportunity
An important step in initiating a high-throughput screening project is selecting the small molecule library to be screened against the…
Radioactivity Assays for Methyltransferases
Methyltransferases have emerged as valuable therapeutic targets in cancer and other pathologies. This enzyme class includes protein and RNA methyltransferases…