SAMDI Mass Spectrometry

Webinar – Integrating Affinity Selection Mass Spectrometry (ASMS) Into a Drug Discovery Workflow

Abstract High-throughput screening remains one of the most powerful, unbiased approaches in drug discovery for revealing novel small molecule modulators…

Development of a Novel Label-Free and High-Throughput Arginase-1 Assay Using Self-Assembled Monolayer Desorption Ionization Mass Spectrometry

Abstract Arginase-1, an enzyme that catalyzes the reaction of L-arginine to L-ornithine, is implicated in the tumor immune response and…

Label-Free Screening of SARS-CoV-2 NSP14 Exonuclease Activity Using SAMDI Mass Spectrometry

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible for the global COVID-19 pandemic. Nonstructural protein 14…

Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic that began in 2019. The…

Ultra High-Throughput Affinity Selection Mass Spectrometry (ASMS) Assays

Publication – A Mass Spectrometric Assay of METTL3/ METTL14 Methyltransferase Activity

Abstract A variety of covalent modifications of RNA have been identified and demonstrated to affect RNA processing, stability, and translation….

Accelerating Drug Discovery from Protein to Cells with Ultra High-Throughput SAMDI Mass Spectrometry

Presentation – An Enabling Label-Free Platform for RNA Drug Discovery Using SAMDI Mass Spectrometry

The Fast and Victorious: Level Up Your Drug Discovery With Innovative Mass Spectrometry

Poster – An Enabling Label-Free Platform for RNA Drug Discovery Using SAMDI Mass Spectrometry