Disrupting Drug Discovery Research From Assay Development to Lead Compound
High-throughput screening remains one of the most powerful, unbiased approaches for small molecule drug discovery. Today, the toolbox for high-throughput…
An Immobilized Enzyme Reactor for Spatiotemporal Control over Reaction Products
An Unusual Salt Effect in an Interfacial Nucleophilic Substitution Reaction
Traceless Immobilization of Analytes for High Throughput Experiments with SAMDI Mass Spectrometry
Abstract: Label-free assays, and particularly those based on the combination of mass spectroscopy with surface chemistries, enable high-throughput experiments of…
Combining SAMDI Mass Spectrometry and Peptide Arrays to Profile Phosphatase Activities
Design of Glycosylation Sites by Rapid Synthesis and Analysis of Glycosyltransferases
SAMDI technology: An innovative approach to high-throughput mass spectrometry
Identification of small molecule noncovalent binders utilizing SAMDI technology
Abstract: In recent years, the ability to unambiguously identify complex mixtures of analytes with high accuracy and resolving power in…