The Fast and Victorious: Level Up Your Drug Discovery With Innovative Mass Spectrometry
An Enabling Label-Free Platform for RNA Drug Discovery Using SAMDI Mass Spectrometry
Mass Spectrometry Gaining Momentum for Biochemical Assay Development and Screening
The goal of drug discovery is clear: reveal chemical matter that generates the most effective response towards a particular target…
Application of MALDI-MS for HTS and SAR
Disrupting Drug Discovery Research From Assay Development to Lead Compound
High-throughput screening remains one of the most powerful, unbiased approaches for small molecule drug discovery. Today, the toolbox for high-throughput…
A Mass Spectrometric Assay for METTL3/14 Methyltransferase Activity
An Immobilized Enzyme Reactor for Spatiotemporal Control over Reaction Products
An Unusual Salt Effect in an Interfacial Nucleophilic Substitution Reaction
Traceless Immobilization of Analytes for High Throughput Experiments with SAMDI Mass Spectrometry
Abstract: Label-free assays, and particularly those based on the combination of mass spectroscopy with surface chemistries, enable high-throughput experiments of…