SAMDI Mass Spectrometry

Label-Free Methyltransferase Assays

Lysine Methyltransferases are enzymes that play a critical role in epigenetic control of gene expression by facilitating transfer of one,…

Nanopatterned Extracellular Matrices Enable Cell-Based Assays with a Mass Spectrometric Readout

Label-Free Arginase Assays

Arginase catalyzes the hydrolysis of L-arginine to L-ornithine and urea. Ornithine serves as the biosynthetic precursor of proline, a critical…

Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase

Label-Free Protease Assays

Proteases are involved in protein processing, regulation of protein function, apoptosis, viral pathogenesis, digestion, photosynthesis, and numerous other essential processes….

An assay based on SAMDI mass spectrometry for profiling protein interaction domains

Machine learning on signal to noise ratios improves peptide array design in SAMDI mass spectrometry

A Bottom-up proteomic approach to identify substrate specificity of outer membrane protease OmpT

Measuring Drug Metabolism Kinetics and Drug-Drug Interactions Using Self-Assembled Monolayers for Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry

Cellular Assays with a Molecular Endpoint Measured by SAMDI Mass Spectrometry